Continued use can lead to physical dependence and - when use is reduced or stopped abruptly- withdrawal symptoms may occur. Because all Prescription sedatives and tranquilizers work by slowing the brain's activity, when an individual stops taking them, there can be a rebound effect, possibly leading to seizures and other harmful consequences. Tolerance to the drug's effects can also occur, meaning that larger doses are needed to achieve similar effects as those experienced initially. This may lead users to take higher doses and risk the occurrence of an overdose.
Addiction can also occur, meaning that users continue to take these drugs despite their harmful consequences.